Supplementary data for Bak et al. 2026 GO virome study

Processed virome and 16S rRNA gene amplicon data supporting the manuscript Gut viral signatures are associated with metabolic phenotypes and weight-loss outcomes after Roux-en-Y gastric bypass.

This directory contains processed data from fecal samples collected before and after bariatric surgery in the Governing Obesity cohort. Viral data were generated from viral-enriched shotgun metagenomes, and prokaryotic community profiles were generated from 16S rRNA gene amplicon sequencing.

Available files

File Description Format Size
GO_viral_genomes.fasta.gz FASTA file containing the 3,013 viral genomes used for downstream analyses. These sequences were estimated to be >50% complete using CheckV. Gzipped FASTA 24 MB
GO_viral_sequences.fasta.gz FASTA file containing viral sequences detected in the current GO cohort after mapping study reads to the viral sequence catalogue. Gzipped FASTA 62 MB
viral_sequence_catalogue.fasta.gz Full viral sequence catalogue generated from viral-enriched fecal metagenomes from this study and additional Danish fecal viral metagenomes. Gzipped FASTA 67 MB
viral_sequence_catalogue_vContact3_taxonomy.csv.gz vContact3-based taxonomic annotation table for the viral sequence catalogue. Gzipped CSV 366 KB
virome_physeq.Rdata R data object containing processed virome profiles for downstream ecological and statistical analyses. RData 456 KB
prokaryotes_physeq.Rdata R data object containing processed 16S rRNA gene ASV profiles representing the prokaryotic microbiota. RData 158 KB

Suggested citation

Please cite the associated manuscript when using these data:

Bak et al. 2026. Gut viral signatures are associated with metabolic phenotypes and weight-loss outcomes after Roux-en-Y gastric bypass.

Contact

For questions about these data, please contact the Arumugam Lab at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.